Willem Einthoven had a long career as professor at
Leiden University, from 1886 until his death in 1927. He was
a physiologist with 'strong clinical interests. To Einthoven the ultimate goal
of physiology was to understand disease and to benefit patients. His main
scientific interests were those of a physicist and naturally his most important
contributions were related to the introduction of physical methods and concepts
that could be relevant for clinical medicine. At the same time he clearly
realized that the potential clinical benefit of research could only be
determined after a period of study and experimentation; in 1906 he wrote a paper
entitled "Het tele-cardiogram" (The tele-cardiogram) in which he
stated: "We should first endeavor to better understand the working of the
heart in all its details, and the cause of a large variety of abnormalities.
This will enable us, in a possibly still-distant future and based upon a clear
insight and improved knowledge, to give relief to the suffering of our
patients." These memorable words have lost nothing of their meaning today
and indeed merit serious consideration in view of the increasing pressure to
produce early results in research. In the first phase of his research career
Einthoven probed into various subjects in the fields of vision and respiration
but later he restricted himself almost entirely to electrical phenomena in
physiology, in particular those related to the heart. To register electrical
currents of the heart he started by using the "Lippmann electrometer"
as Waller had done before him. Despite Einthoven's improvements, this instrument
failed to satisfy his high standards for accuracy so he soon felt compelled to
design a new instrument, the string galvanometer. He achieved such perfection
that many modern electrocardiographs, incorporating the latest technological
developments in electronics, do not attain equally reliable and undistorted
electrocardiographic recordings. Einthoven could not have done this without his
characteristic unbounded capacity for concentration on the problems he was
confronted with and an almost prophetic insight into the future clinical
significance of the electrocardiogram. Today, the electrocardiogram having
evolved into the most widely applied diagnostic tool in patients with diseases
of the heart, it is difficult to realize that Einthoven, as he stated himself,
still had to prove that diseases of the heart would lead to abnormalities
recognizable in the electrocardiogram. In addition to setting the groundwork of
this field by constructing the first instrument capable of accurate recording he
developed a system of standardization which continues to be followed all over
the world. The significance of this for the development of diagnostic
electrocardiography can hardly be overestimated. Einthoven's
contributions to the field were recognized in 1924 when he received the Nobel
Prize. lt is characteristic of his modesty that accepting the prize he pointed
out that the development of electrocardiography had only been made possible by
concerted efforts of many workers in this field, among whom he especially
mentioned his British friend, Thomas Lewis. THE EINTHOVEN FOUNDATION
The Einthoven Foundation
was established in 1979. The board of the Einthoven Foundation and its
international advisory board now make proposals for potential recipients of the
Einthoven Awards. One of the Major activities of the Einthoven Foundation is the
organization of congresses and seminars in which recent developments in
cardiology, cardiovascular surgery, and related areas are placed in historical perspective. The Einthoven Lectures are
generally part of those meetings but on special occasions the lectures are held
separately. Programs are planned to stimulate young investigators who perform
original clinical and fundamental research related to the heart and blood
vessels. The Einthoven Foundation also encourages the publication of scientific
or otherwise enlightening material that may, in a broad sense, serve the
preservation of the history of developments in the field of cardiology.
HOW TO SUPPORT THE EINTHOVEN FOUNDATION? The
Einthoven Foundation is a non-profit organization which is entirely dependent on
donations, legacies, and other gifts. An annual donation of a
minimum of Dfl 500,- gives the donor the status of Friend of the Einthoven
Foundation which includes free access to the Einthoven lectures and some of the
other activities organized by the Einthoven Foundation. Donations of more than Dfl 5000,- entitle the Donor to the same
privileges in a lifelong capacity and official recognition in the Register of
Contributors. Correspondence:
Einthoven Foundation M. Bootsma,
MD, PhD, Secretary Bank account: 598.28.6195 (Stichting Einthoven, Leiden, The Netherlands)Email: info@einthoven.nlBoard of the
Einthoven Foundation
M.J. Schalij, Chairman
Advisory board of the Einthoven
Foundation
G.H. Bieger, Baltimore, USA THE
EINTHOVEN LECTURES AND THE EINTHOVEN AWARD
To commemorate its Nobel
Prize Laureate, in 1956 the University of Leiden established the Einthoven
Lecture and Einthoven Award. lt was decided to organize this event biennially
and to present the Einthoven Award to a physician of international renown who
had made outstanding contributions to the field of cardiology, including
fundamental as well as clinical aspects. The first speaker was Dr Paul Dudley
White, a recognized pioneer in clinical cardiology and a gifted teacher, who was
to be followed by many other scientists and clinicians of equal esteem (see
below). Traditionally the award is presented by the Rector of the University in
a typical academic setting and in the presence of members of the Einthoven
family.
THE EINTHOVEN LECTURES |
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