Synopsis (2)

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Study Population

Patients that are candidates for heart failure surgery in which restrictive mitral valve repair (RMA) is always part of the procedure and patients that are candidates for mitral valve repair for prolapse disease will be included. A total of 80 patients will be divided in 4 groups of 20 patients. Patients with pre-existent heart failure are divided in three groups: RMA + LV-reconstruction (Dor-like procedure) ± CABG, RMA + CorCap and RMA + CABG. The control group embraces patients without heart failure, namely mitral valve repair for prolapse disease.

Study Procedures

After giving their informed consent to participate in this study blood samples and biopsies will be taken during the operation and perioperative. Anaesthetic procedures in all groups will be carried out according tot standard care. Various established markers in blood and tissue will be studied.

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